A 24-year-old with 4 days of watery diarrhea after clindamycin has positive NAAT for C. difficile. First episode, non-severe. Best initial therapy?...

Question

A 24-year-old with 4 days of watery diarrhea after clindamycin has positive NAAT for C. difficile. First episode, non-severe. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg bid 10 days

Answer

Oral vancomycin 125 mg qid 10 days

Answer

Metronidazole 500 mg tid 10 days

Answer

Probiotics alone

Answer

Tapered vancomycin immediately

us-abfm MCQ (SBA): C. difficile Infection