A 61-year-old man with CKD G3a (eGFR 50) and albuminuria 120 mg/g starts an SGLT2 inhibitor. He notes an eGFR decline from 50 to 45 over two weeks wit...

Question

A 61-year-old man with CKD G3a (eGFR 50) and albuminuria 120 mg/g starts an SGLT2 inhibitor. He notes an eGFR decline from 50 to 45 over two weeks without symptoms. What should be done?

Accepted Answer

Continue; a small initial eGFR dip is expected and not a reason to stop

Answer

Stop SGLT2 inhibitor immediately

Answer

Add NSAID for renal perfusion

Answer

Double SGLT2 dose

Answer

Start IV fluids routinely

us-abfm MCQ (SBA): SGLT2 eGFR Dip

A 61-year-old man with CKD G3a (eGFR 50) and albuminuria 120 mg/g starts an SGLT2 inhibitor. He notes an eGFR decline from 50 to 45 over two weeks without symptoms. What should be done?