A 50-year-old presents with watery diarrhea after recent antibiotics; stool tests positive for toxigenic C. difficile. First episode, non-severe. Pref...

Question

A 50-year-old presents with watery diarrhea after recent antibiotics; stool tests positive for toxigenic C. difficile. First episode, non-severe. Preferred therapy?

Accepted Answer

Fidaxomicin 200 mg BID 10 days

Answer

Metronidazole 500 mg TID for 10 days

Answer

Vancomycin 125 mg QID 10 days (preferred over fidaxomicin)

Answer

Rifaximin 550 mg TID 14 days

Answer

Probiotics only

us-abfm MCQ (SBA): Clostridioides difficile Infection

A 50-year-old presents with watery diarrhea after recent antibiotics; stool tests positive for toxigenic C. difficile. First episode, non-severe. Preferred therapy?