A 58-year-old with tophaceous gout and recurrent flares chooses urate-lowering therapy. Best target and initial agent?...

Question

A 58-year-old with tophaceous gout and recurrent flares chooses urate-lowering therapy. Best target and initial agent?

Accepted Answer

Target serum urate

Answer

No target; fixed-dose allopurinol

Answer

Start probenecid first-line regardless of renal function

Answer

Start pegloticase first-line

us-abim MCQ (SBA): Gout (ULT)