A 35-year-old patient with classic dyspepsia and no alarm features tests positive for H. pylori and completes optimized 14-day bismuth quadruple thera...

Question

A 35-year-old patient with classic dyspepsia and no alarm features tests positive for H. pylori and completes optimized 14-day bismuth quadruple therapy. When should test-of-cure be obtained and how?

Accepted Answer

≥4 weeks after completion of antibiotics and ≥2 weeks off PPI using urea breath test or stool antigen

Answer

Immediately after therapy with stool antigen while on PPI

Answer

Only if symptoms persist

Answer

Repeat serology at 4 weeks

Answer

Endoscopy with biopsy for all patients at 2 weeks

us-abfm MCQ (SBA): H. pylori-Test of Cure

A 35-year-old patient with classic dyspepsia and no alarm features tests positive for H. pylori and completes optimized 14-day bismuth quadruple therapy. When should test-of-cure be obtained and how?