A 60-year-old woman with a history of hypertension and obesity presents with persistent cough and exertional dyspnea. Spirometry confirms COPD with fr...

Question

A 60-year-old woman with a history of hypertension and obesity presents with persistent cough and exertional dyspnea. Spirometry confirms COPD with frequent exacerbations (≥2 moderate in the past year) despite LAMA. Blood eosinophils are 380/µL. What pharmacologic escalation is supported by guideline evidence?

Accepted Answer

Escalate to triple therapy (ICS/LABA/LAMA)

Answer

Add LABA only

Answer

Switch to ICS monotherapy

Answer

Add theophylline

Answer

Start roflumilast instead of inhaled therapies

us-usmle-step-2 MCQ (SBA): COPD