A 76-year-old taking apixaban for atrial fibrillation develops haemodynamic instability from an upper gastrointestinal haemorrhage. Endoscopic haemost...

Question

A 76-year-old taking apixaban for atrial fibrillation develops haemodynamic instability from an upper gastrointestinal haemorrhage. Endoscopic haemostasis and major-haemorrhage support have not controlled the bleeding, and the last apixaban dose was 4 hours ago. Which specific reversal agent is recommended by NICE?

Accepted Answer

Administer intravenous andexanet alfa

Answer

Administer four-factor prothrombin complex concentrate

Answer

Administer intravenous idarucizumab

Answer

Administer intravenous phytomenadione

Answer

Administer intravenous protamine sulfate

DOAC Reversal (Factor Xa) — MRCP Part 1 MCQ