A 27-year-old MSM with a bacterial STI in the past year asks about doxycycline postexposure prophylaxis after condomless sex. What regimen and follow-...

Question

A 27-year-old MSM with a bacterial STI in the past year asks about doxycycline postexposure prophylaxis after condomless sex. What regimen and follow-up align with guidance?

Accepted Answer

No role for antibiotic PEP for STIs

Answer

Doxycycline 100 mg once within 24 hours; no follow-up needed

Answer

Doxycycline 200 mg once within 72 hours after sex (max 200 mg/24 h) with STI screening every 3-6 months

Answer

Doxycycline 100 mg BID for 7 days after each exposure

Answer

Azithromycin 1 g once after exposure

us-abfm MCQ (SBA): STI Prevention (doxy-PEP)

A 27-year-old MSM with a bacterial STI in the past year asks about doxycycline postexposure prophylaxis after condomless sex. What regimen and follow-up align with guidance?