A 34-year-old man with primary syphilis (painless chancre, RPR reactive) has no penicillin allergy. Best treatment?...

Question

A 34-year-old man with primary syphilis (painless chancre, RPR reactive) has no penicillin allergy. Best treatment?

Accepted Answer

Ceftriaxone 250 mg IM once

Answer

Doxycycline 100 mg BID for 14 days

Answer

Azithromycin 2 g PO once

Answer

Benzathine penicillin G 2.4 million units IM once

Answer

Penicillin V 500 mg PO QID for 10 days

us-abfm MCQ (SBA): Syphilis