A 63-year-old with T2D and CKD eGFR 32 mL/min/1.73 m² is taking metformin 1,000 mg BID. What is appropriate regarding metformin?...

Question

A 63-year-old with T2D and CKD eGFR 32 mL/min/1.73 m² is taking metformin 1,000 mg BID. What is appropriate regarding metformin?

Accepted Answer

Continue while eGFR ≥30; discontinue if eGFR falls

Answer

Continue at same dose indefinitely

Answer

Increase dose to maintain A1c goal

Answer

Stop at eGFR

Answer

Use metformin regardless of eGFR because lactic acidosis is rare

us-usmle-step-2 MCQ (SBA): Metformin-CKD Threshold