A 42-year-old kidney-transplant recipient has latent drug-sensitive tuberculosis after active disease is excluded. Preventive treatment is indicated, ...

Question

A 42-year-old kidney-transplant recipient has latent drug-sensitive tuberculosis after active disease is excluded. Preventive treatment is indicated, but tacrolimus creates a major concern about rifamycin interactions. Which NICE regimen best avoids that interaction?

Accepted Answer

Give isoniazid with pyridoxine for 6 months

Answer

Give isoniazid with rifampicin for 3 months

Answer

Give rifampicin monotherapy for 4 months

Answer

Give pyrazinamide with ethambutol for 6 months

Answer

Give rifabutin monotherapy for 3 months

Metformin in CKD — MRCP Part 1 MCQ

A 42-year-old kidney-transplant recipient has latent drug-sensitive tuberculosis after active disease is excluded. Preventive treatment is indicated, but tacrolimus creates a major concern about rifamycin interactions. Which NICE regimen best avoids that interaction?