A 25-year-old transgender woman with multiple male partners seeks HIV prevention. HIV test today is negative; eGFR is normal. What is the best next st...

Question

A 25-year-old transgender woman with multiple male partners seeks HIV prevention. HIV test today is negative; eGFR is normal. What is the best next step?

Accepted Answer

Start daily oral tenofovir DF/emtricitabine (TDF/FTC) after confirming HIV negative and renal function

Answer

Start lamivudine/tenofovir DF today

Answer

Offer PrEP only if condom use is inconsistent

Answer

Start post-exposure prophylaxis for 28 days

Answer

Defer PrEP until a fourth‑generation test is repeated in 3 months

us-usmle-step-2 MCQ (SBA): HIV Preexposure Prophylaxis

A 25-year-old transgender woman with multiple male partners seeks HIV prevention. HIV test today is negative; eGFR is normal. What is the best next step?