A 62-year-old man with recurrent gout and tophi starts allopurinol. What prophylaxis is recommended during urate-lowering initiation?...

Question

A 62-year-old man with recurrent gout and tophi starts allopurinol. What prophylaxis is recommended during urate-lowering initiation?

Accepted Answer

Low-dose colchicine or NSAID to prevent flare during initiation

Answer

No prophylaxis needed

Answer

High-dose prednisone for months

Answer

Antibiotics

Answer

Immediate allopurinol discontinuation if asymptomatic

us-abfm MCQ (SBA): Flare Prophylaxis with ULT