A 60-year-old with AF and eGFR 80 mL/min/1.73 m² takes apixaban 5 mg BID. He asks if dose should be reduced due to age alone. What is correct?...

Question

A 60-year-old with AF and eGFR 80 mL/min/1.73 m² takes apixaban 5 mg BID. He asks if dose should be reduced due to age alone. What is correct?

Accepted Answer

Reduce only if ≥2 of: age ≥80

Answer

Reduce to 2.5 mg BID at age ≥60

Answer

weight ≤60 kg

Answer

creatinine ≥1.5 mg/dL

Answer

Reduce for any creatinine ≥1.0

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