A 58-year-old nonpregnant adult with positive syphilis serology (RPR 1:16) and no neurologic symptoms. Early syphilis suspected. Preferred regimen?...

Question

A 58-year-old nonpregnant adult with positive syphilis serology (RPR 1:16) and no neurologic symptoms. Early syphilis suspected. Preferred regimen?

Accepted Answer

Benzathine penicillin G 2.4 million units IM once

Answer

Doxycycline 100 mg BID for 14 days

Answer

Azithromycin 2 g PO once

Answer

Ceftriaxone 1 g IV daily for 14 days

Answer

No treatment until confirmatory treponemal test

us-usmle-step-2 MCQ (SBA): Syphilis (Early)