A 58-year-old with a first episode of non-severe Clostridioides difficile infection (WBC 12,000/µL, creatinine normal). Preferred initial therapy?...

Question

A 58-year-old with a first episode of non-severe Clostridioides difficile infection (WBC 12,000/µL, creatinine normal). Preferred initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO BID for 10 days (preferred)

Answer

Metronidazole 500 mg PO TID for 10 days

Answer

Vancomycin 125 mg PO QID for 10 days (preferred)

Answer

Bezlotoxumab monotherapy

Answer

Probiotics alone

us-usmle-step-2 MCQ (SBA): Clostridioides difficile Infection