A 50-year-old with AF, BMI 78 kg, and creatinine 1.0 mg/dL is considered for apixaban. Which dosing factor would trigger dose reduction?...

Question

A 50-year-old with AF, BMI 78 kg, and creatinine 1.0 mg/dL is considered for apixaban. Which dosing factor would trigger dose reduction?

Accepted Answer

Serum creatinine ≥1.5 mg/dL plus age ≥80 or weight ≤60 kg (need ≥2 criteria)

Answer

Age ≥75 years alone

Answer

Weight ≥60 kg

Answer

Any CKD stage

Answer

Concomitant aspirin use

us-usmle-step-2 MCQ (SBA): Atrial Fibrillation