A patient with moderate chronic kidney impairment is undergoing primary elective knee replacement. Tranexamic acid is planned to minimise operative bl...

Question

A patient with moderate chronic kidney impairment is undergoing primary elective knee replacement. Tranexamic acid is planned to minimise operative blood loss. Which regimen follows NICE?

Accepted Answer

Reduced-dose intravenous tranexamic acid without topical tranexamic acid

Answer

Full-dose intravenous plus topical tranexamic acid up to a combined 3 g

Answer

Topical tranexamic acid without an intravenous dose

Answer

Full-dose intravenous tranexamic acid followed by a postoperative infusion

Answer

Oral tranexamic acid followed by topical tranexamic acid at wound closure

DOAC Reversal — MRCP Part 1 MCQ

A patient with moderate chronic kidney impairment is undergoing primary elective knee replacement. Tranexamic acid is planned to minimise operative blood loss. Which regimen follows NICE?