A 60-year-old with suspected C. difficile recurrence after initial vancomycin course (now day 10 post-therapy) has watery diarrhea and positive toxin ...

Question

A 60-year-old with suspected C. difficile recurrence after initial vancomycin course (now day 10 post-therapy) has watery diarrhea and positive toxin EIA. Next-best therapy?

Accepted Answer

Fidaxomicin 200 mg BID for 10 days

Answer

Repeat vancomycin 125 mg QID for 10 days

Answer

Metronidazole 500 mg TID for 10 days

Answer

Probiotics plus loperamide

Answer

Fecal microbiota transplantation as first-line

us-usmle-step-2 MCQ (SBA): Recurrent C. difficile infection

A 60-year-old with suspected C. difficile recurrence after initial vancomycin course (now day 10 post-therapy) has watery diarrhea and positive toxin EIA. Next-best therapy?