A 58-year-old man presents with progressive proximal muscle weakness and elevated CK after starting high-dose statin and clarithromycin for pneumonia....

Question

A 58-year-old man presents with progressive proximal muscle weakness and elevated CK after starting high-dose statin and clarithromycin for pneumonia. Most likely mechanism?

Accepted Answer

Statin-macrolide interaction via CYP3A4 inhibition

Answer

Viral myositis

Answer

Autoimmune polymyositis

Answer

Vitamin D deficiency

Answer

Electrolyte imbalance

prescribing safety assessment MCQ (SBA): Drug Interaction Myopathy

A 58-year-old man presents with progressive proximal muscle weakness and elevated CK after starting high-dose statin and clarithromycin for pneumonia. Most likely mechanism?