A 64-year-old man on once-daily gentamicin for Gram-negative sepsis has rising creatinine. Which statement is correct?...

Question

A 64-year-old man on once-daily gentamicin for Gram-negative sepsis has rising creatinine. Which statement is correct?

Accepted Answer

Monitor trough levels to minimise toxicity

Answer

Peak level guides nephrotoxicity risk

Answer

Ototoxicity correlates with low troughs

Answer

Switch to vancomycin for less nephrotoxicity

Answer

No monitoring needed with once-daily dosing

prescribing safety assessment MCQ (SBA): Aminoglycoside Toxicity