A 76-year-old man with atrial fibrillation on apixaban requires urgent laparotomy for perforated ulcer. Last dose 6 hours ago. Renal function normal. ...

Question

A 76-year-old man with atrial fibrillation on apixaban requires urgent laparotomy for perforated ulcer. Last dose 6 hours ago. Renal function normal. What is the most appropriate reversal strategy pre-op?

Accepted Answer

Prothrombin complex concentrate (off-label) and consider tranexamic acid

Answer

Vitamin K IV

Answer

Idarucizumab

Answer

Fresh frozen plasma only

Answer

Protamine sulfate

mrcp part 1 MCQ (SBA): DOAC Reversal (Perioperative)

A 76-year-old man with atrial fibrillation on apixaban requires urgent laparotomy for perforated ulcer. Last dose 6 hours ago. Renal function normal. What is the most appropriate reversal strategy pre-op?