A 50-year-old woman presents with fatigue and pruritus. LFTs reveal: ALP 450 U/L (30-130), GGT 300 U/L, ALT 60 U/L. Ultrasound abdomen is normal. Whic...

Question

A 50-year-old woman presents with fatigue and pruritus. LFTs reveal: ALP 450 U/L (30-130), GGT 300 U/L, ALT 60 U/L. Ultrasound abdomen is normal. Which specific autoantibody is most strongly associated with the likely diagnosis?

Accepted Answer

Anti-mitochondrial antibodies (AMA)

Answer

Anti-CCP antibodies

Answer

Anti-nuclear antibodies (ANA)

Answer

Anti-smooth muscle antibodies (ASMA)

Answer

p-ANCA

mrcp part 1 MCQ (SBA): Primary Biliary Cholangitis (PBC)

A 50-year-old woman presents with fatigue and pruritus. LFTs reveal: ALP 450 U/L (30-130), GGT 300 U/L, ALT 60 U/L. Ultrasound abdomen is normal. Which specific autoantibody is most strongly associated with the likely diagnosis?