A 30-year-old primigravida presents at 32 weeks gestation with generalised itching, particularly severe on the palms and soles, worse at night. There ...

Question

A 30-year-old primigravida presents at 32 weeks gestation with generalised itching, particularly severe on the palms and soles, worse at night. There is no rash. Liver function tests show elevated ALT, AST, and significantly raised bile acids. What is the most likely diagnosis?

Accepted Answer

Intrahepatic cholestasis of pregnancy (ICP)

Answer

PUPPP (Pruritic Urticarial Papules and Plaques of Pregnancy)

Answer

Pemphigoid gestationis

Answer

Acute fatty liver of pregnancy

Answer

Viral hepatitis

ukmla MCQ (SBA): Intrahepatic Cholestasis of Pregnancy (ICP)

A 30-year-old primigravida presents at 32 weeks gestation with generalised itching, particularly severe on the palms and soles, worse at night. There is no rash. Liver function tests show elevated ALT, AST, and significantly raised bile acids. What is the most likely diagnosis?