A patient stable on clozapine 400 mg daily smokes 20 cigarettes a day. On admission to a smoke-free ward he stops smoking and starts nicotine replacement. Which prescribing plan best prevents clozapine toxicity?AContinue nicotine replacement and ask the mental-health team to review the clozapine dose and plasma levelBContinue nicotine replacement and increase the clozapine dose to offset loss of nicotine enzyme inductionCStop nicotine replacement and maintain the clozapine dose while tobacco withdrawal symptoms are observedDReplace nicotine replacement with vaping and maintain the clozapine dose during the smoke-free admissionEOmit clozapine for 48 hours and restart the full dose once tobacco cravings have settledCheck my answer