A 33-year-old female IV drug user is found to have fever, new regurgitant murmur, and multiple septic emboli. Blood cultures grow Staphylococcus aureu...

Question

A 33-year-old female IV drug user is found to have fever, new regurgitant murmur, and multiple septic emboli. Blood cultures grow Staphylococcus aureus. Echocardiogram confirms tricuspid regurgitation. Which antibiotic regimen is indicated first-line?

Accepted Answer

IV flucloxacillin or IV vancomycin (if MRSA suspected)

Answer

Oral flucloxacillin

Answer

Oral amoxicillin plus gentamicin

Answer

IV penicillin V

Answer

High-dose oral co-trimoxazole

MCQ (SBA): Endocarditis

A 33-year-old female IV drug user is found to have fever, new regurgitant murmur, and multiple septic emboli. Blood cultures grow Staphylococcus aureus. Echocardiogram confirms tricuspid regurgitation. Which antibiotic regimen is indicated first-line?