A 72-year-old man presents with progressive exertional breathlessness and ankle swelling. An echocardiogram confirms heart failure with reduced ejecti...

Question

A 72-year-old man presents with progressive exertional breathlessness and ankle swelling. An echocardiogram confirms heart failure with reduced ejection fraction (HFrEF). According to NICE, which class of medication is indicated as first-line therapy alongside a diuretic for symptomatic relief?

Accepted Answer

ACE inhibitor (or ARB) plus beta-blocker

Answer

Digoxin

Answer

Aldosterone antagonist (e.g. spironolactone)

Answer

Hydralazine and nitrate combination

Answer

Ivabradine

Heart failure with reduced ejection fraction (HFrEF) — UKMLA MCQ

A 72-year-old man presents with progressive exertional breathlessness and ankle swelling. An echocardiogram confirms heart failure with reduced ejection fraction (HFrEF). According to NICE, which class of medication is indicated as first-line therapy alongside a diuretic for symptomatic relief?