A 32-year-old woman has fatigue, joint pain, and a malar rash sparing the nasolabial folds. She is ANA- and anti-dsDNA-positive. According to NICE, wh...

Question

A 32-year-old woman has fatigue, joint pain, and a malar rash sparing the nasolabial folds. She is ANA- and anti-dsDNA-positive. According to NICE, which is the mainstay of induction therapy for active moderate systemic lupus erythematosus (SLE)?

Accepted Answer

High-dose oral corticosteroids plus immunosuppressant (e.g. mycophenolate)

Answer

High-dose IV methylprednisolone only

Answer

NSAIDs alone

Answer

Antimalarials (hydroxychloroquine) alone

Answer

IV cyclophosphamide for all mild flares

Systemic Lupus Erythematosus (SLE) — MRCP Part 1 MCQ

A 32-year-old woman has fatigue, joint pain, and a malar rash sparing the nasolabial folds. She is ANA- and anti-dsDNA-positive. According to NICE, which is the mainstay of induction therapy for active moderate systemic lupus erythematosus (SLE)?