Prion Diseases

Overview of CJD and other prion diseases.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)

Last reviewed: 21 October 2025

Neurology

Clinical Guidelines

CHMP position statement on Creutzfeldt-Jakob disease and plasma-derived and urine-derived medicinal products (EMA)

CHMP position statement on Creutzfeldt-Jakob disease and plasma-derived and urine-derived medicinal products (Revision 2)

EFNS-ENS Guidelines on the diagnosis and management of disorders associated with dementia

Health Technical Memorandum 01-01. Part A: Management and decontamination of surgical instruments (medical devices) used in acute care

Infection control of CJD, vCJD and other human prion diseases in healthcare and community settings (ACDP TSE Risk Management Subgroup Guidance)

World Health Organization: WHO infection control guidelines for transmissible spongiform encephalopathies (TSEs)

World Health Organization: WHO infection control guidelines for transmissible spongiform encephalopathies (TSEs), including prion diseases

2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings

Clinical Testing Guidance for Blood Safety: Prion Diseases

Disinfection and Sterilization of Prion-Contaminated Medical Instruments (SHEA Guideline)

EFNS-ENS Guidelines on the diagnosis and management of disorders associated with dementia

Guideline for disinfection and sterilization of prion-contaminated medical instruments

Guidelines for Environmental Infection Control in Health-Care Facilities

Prion Disease Reporting and Investigation Guideline

Review of guidelines for prevention of Creutzfeldt–Jakob disease transmission in healthcare settings (ECDC)